Studies in natural products chemistry volume 12: stereoselective synthesis part h reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes the synthetic methodology for 2-amino alcohols of biological interest and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents isolation structure elucidation biosynthesis and biological activity of the avermectins two-stage coupling process of macrolide antibiotics synthesis and synthesis of the rifamycin s ansa-chain compound. The complete synthesis of erythromycin a is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an a-ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists biologists students and researchers.
Brand: Elsevier Science
Size: []
